This trend of intermixing CGI and cell animation has been met with mixed results, some good some bad. Blassreiter, to me, falls into the former catagory. The series, about the inevitable fall of the human race via alien-like creatures (read: government conspiracy, in Germany no less!) is enhanced through the fluid movement and imposing like of the CGI effect.
Then there's the story. Difficult to describe and so, so dark in theme it's just right up our ally. We have a stab at it in the full description.
We really enjoyed the first-half of this series from Gonzo. Directed by Ichiro ITANO (Fist of the North Star).